Fats Toxins can also originate from the gut i.e., breakdown products of metabolism, including hormones, internal toxins such as metabolites of yeast [d-arabinitol], or gut bacteria.
The role of toxins in obesity development and later fat loss is becoming increasingly concerning as the emerging evidence forms a plausible link between toxins and obesity. Exposure to toxins comes from two main sources: the environment (external or exogenous toxins), which includes environmental pollutants such as pesticides, industrial compounds, solvents, detergents, plasticizers, cosmetic additives, chemical additives, colorings, preservatives, flavorings, microbial toxins such as aflatoxins from peanuts, mycotoxins from molds, and bisphenol A found in plastic baby bottles, toys, and especially dental sealants; and “lifestyle chemicals,” such as alcohol, OTC drugs, and prescription drugs. It can be byproducts from food preparation such as acrylamide from French fries, nitrosamines from cold cuts and sausages, polycyclic aromatic hydrocarbons (PCAHs) from charbroiled meats, trans fats from partial hydrogenation of fats and AGEs (advanced glycosylated end products) in foods in which the glucose molecule is brought to high temperatures. Toxins can also originate from the gut i.e., breakdown products of metabolism, including hormones, internal toxins such as metabolites of yeast [d-arabinitol], or gut bacteria
Both sources of toxins can overload the body’s endogenous detoxification mechanisms. When this happens, these toxins, which are often fat soluble and have an affinity for adipose tissue, are ultimately stored in the body’s depot fat. This can necessitate the deposition of more fat and obesity development, or in the case of weight or fat loss, the release of these toxins can interfere with the body’s functioning, placing a burden on the liver and even its ability to continue to lose more fat (Barouki, 2010; La Merrill, 2013; Tremblay et al, 2004).
Toxins alter metabolism, disrupt endocrine function, damage the mitochondria, increase inflammation and oxidative stress, lower thyroid hormones, and alter circadian rhythms and the autonomic nervous system. These all interfere with key weight control mechanisms in the body. Using a comprehensive approach to obesity, including the assessment and treatment of toxin-mediated effects can result in more effective body fat and weight management. Simple lifestyle choices, as well as medical detoxification, can reduce exposure to toxins and enhance mobilization and elimination of stored and external toxins
Thesis and reports by Sheila Dean, DSc, RDN, LD, CCN, CDE.
This Article is written by Nutrition Student, ‘Syeda Ruhina Raushan’